[PDF] Top 20 Update on Chagas Disease in Venezuela – A Review

... Chagas disease, caused by the Kinetoplastida ha- emoflagellate protozoa Trypanosoma cruzi, is one of the most important endemic pathologies in ...parasitic disease below malaria and ... See full document

... Based on these assumptions, we began to study T. cruzi infection in ancient populations from North and South America, using molecular biology techniques to recover genetic material from the parasite ... See full document

... kidney disease (ADPKD) is the most common inherited ...depending on the main factors of progression (genetic, renal volume, and ...choice in the screening for relatives of ADPKD ...necessary, ... See full document

... Chagas disease is considered the most neglected of the neglected tropical diseases, a fact that can be demonstrated within the context of ...treatment. In the 1970s, two drugs that act by forming ... See full document

... provided in the ...fied in a standardized ...published in indexed journals, and consequently end up not being cited by other ...prevalences. In addition, studies were conducted between 1980 ... See full document

... 5 For our purposes, we define susceptible, tolerant, and resistant bugs as follows: susceptible bugs yield mortal- ity data comparable to those obtained with their labo[r] ... See full document

... of Chagas’ disease (PCDT) can ...periodic update and revision of the national guidelines for diagnosis, treatment and monitoring of individuals infected and their different stages and clinical ... See full document

... dilation in the Syrian hamster model of CCC (BILATE et al., 2003). However, in spite of the substantial evidence supporting a role for immune responses in myocardial damage, the nature of the antigen ... See full document

... difference in the mean age among the groups. In addition, few studies were included in each meta- ...included in the meta-analysis was high for the comparison between non-dilated CHD and ... See full document

... described in BO, only the presence of intestinal metaplasia with goblet cells seems to be indispensable for an accurate ...Surveillance in BO is still controversial and, to date, the endoscopic screening is ... See full document

... present in the Andean sub-region (for different rea- sons) has been slow and control interventions have still not been installed in all geographical areas occupied by the target ...applied in the ... See full document

... interest in Chagas dis- ease research apparently developed, since the number and kind of publications from national and international authors increased ...dramatically. In different universities from ... See full document

... tor in 2008. In El Salvador, housing improvements, as- sociated with controlling the malaria vector by means of insecticides, resulted in elimination of ...found in that ...found in ... See full document

... Chagas disease is a protozoan infection that was identified over a century ...the disease. Success of a drug design is dependent on correct biological ...for Chagas disease, it ... See full document

... of Chagas disease research and control activities ...abundant in those areas, heavily infesting rural houses with palm fiber ...and Chagas disease prevalence rates are rela- tively ... See full document

... activities in infected people on the overall activities of prevention and ...have on the quality of life of the patients, with the conse- quent reduction of the burden of the disease by ... See full document

... present in different families of plants and in some of them have been used in folk medicine for the treatment of diseases, especially ...contaminants in the process of lapachol ...(reviewed ... See full document

... of Chagas disease) in endemic areas, major differences seem to occur among the different ...performed in endemic countries located in the South Cone of Latin ...detected in 431 ... See full document

... BZL, in addition to having trypanocidal activity, acts as an immunomod- ...Moreover, in a rat model of acute ...depend on both trypanocidal action and immunomodulating effects ...TNF-␣ in ... See full document

... exists, in which landscapes consist of grasslands with scattered broad-leaved evergreen trees and costal plains, covering about 263,512 ...1990-98 in the States of Barinas and Portuguesa. In this ... See full document