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Structure and Phase State of Bone Apatite of Calcified Aortic Fragments with Osteoporosis

Ya.V. Khyzhnya

1

, A.V. Ataman

1

, A.S. Stanislavov

2

, V.N. Kuznetsov

2

, S.M. Danilchenko

2

1

Sumy State University, 2, R.-Korsakov Str., 40007 Sumy, Ukraine

2

Institute for Applied physics, NAS of Ukraine, 58, Petropavlovskaya Str., 40000 Sumy, Ukraine

The paper represents the results of the study on the structure and phase composition of bone apatite and fragments of calcified aorta of the same experimental animal with model osteoporosis. Examination by the X-ray and electron diffraction, electron microscopy and infrared spectroscopy reveals that pathological calcification of rabbit aorta with model osteoporosis in crystal-chemicalterms is the imperfect calcium apa-tite Ca10(PO4)6(OH)2. Temperature growth of ectopic apatite crystals during annealing at 900C is similar

to bioapatite of bone.

Keywords: Structure, Phase composition, Bone apatite, Osteoporosis.

1. R.S. Braithwaite, N.F. Col, J.B. Wong, J. Am. Geriatr. Soc.51, 364 (2003).

2. D.P. Kiel, L.I. Kauppila, L.A. Cupples, Calcif. Tissue Int. 68, 271 (2001).

3. E. Schulz, K. Arfai, X. Liu, J. Sayre, V. Gilsanz, J. Clin.

Endocrinol. Metab.89, 4246 (2004).

4. D.M. Kado, W.S. Browner, T. Blackwell, R. Gore, J. Bone

Miner. Res. 15, 1974 (2000).

5. T. Yamaguchi, T. Sugimoto, S. Yano, et al., Endocr. J.49, 211 (2002).

6. K.S.G.Jie, M.L. Bots, C. Vermeer, J.C.M. Witteman, D.E. Grobbee,Calcif. Tissue Inter.59,352 (1996). 7. A.E. Hak, H.A. Pols, A.M. van Hemert, A. Hofman,

J.C. Witteman, Arterioscler Thromb Vasc. Biol. 20, 1926

(2000).

8. L.L. Demer, Circulation 92, 2029 (2005).

9. P.A. Price, S.A. Faus, M.K. Williamson, Arterioscler Thromb Vasc. Biol. 21, 817 (2001).

10. M. Abedin, Y. Tintut, L.L. Demer, Arterioscler Thromb

Vasc. Biol. 24, 1161 (2004).

11. T.M. Doherty, L.A. Fitzpatrick, F. Inoue, Endocr. Rev.25, 629 (2004).

12. S.I. McFarlane, R. Muniyappa, J.J. Shin, G. Bahitiyar, J.R. Sowers, Endocrine23, 1 (2004).

13. M.R.Rubin, S.J. Silverberg, J. Clin. Endocrin. Metab.89, 4243 (2004).

14. T.M. Doherty, K. Asotra, L.A. Fitzpatrick, PNAS 100, 11203 (2003).

15. L.I. Demer, Int. J. Epidemiol.31, 737 (2002).

16. S.N. Danilchenko, A.V. Koropov, I.Yu. Protsenko, B. Sulkio-Cleff, L.F. Sukhodub, Cryst. Res. Technol.41, 263 (2006). 17. S.N. Danilchenko, I.Yu. Protsenko, L.F. Sukhodub, Cryst.

Res. Technol.44, 553 (2009).

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