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Drugs - Resistance

Previous use of quinolones: a surrogate marker for first line anti-tuberculosis drugs resistance in HIV-infected patients?

Previous use of quinolones: a surrogate marker for first line anti-tuberculosis drugs resistance in HIV-infected patients?

... antituberculosis drugs was defined as any anti-TB treatment started before ...Primary resistance was defined as resistance in isolates from patients who did not have history of TB ...drug ...

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Early responses of the STAT3 pathway to platinum drugs are associated with cisplatin resistance in epithelial ovarian cancer

Early responses of the STAT3 pathway to platinum drugs are associated with cisplatin resistance in epithelial ovarian cancer

... transient resistance, some early events might contribute to the onset of acquired chemoresistance in ovarian cancer ...of resistance may represent physiologi- cal adaptation at the multicellular level, ...

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Beef Carcass Contamination by Shiga Toxin-Producing Escherichia coli Strains in an Abattoir in Brazil: Characterization and Resistance to Antimicrobial Drugs

Beef Carcass Contamination by Shiga Toxin-Producing Escherichia coli Strains in an Abattoir in Brazil: Characterization and Resistance to Antimicrobial Drugs

... antimicrobial resistance may become a major problem in veterinary medicine as a consequence of the intensive use or misuse of antimicrobial drugs (Monroe and Polk, ...of resistance situation in a ...

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Genotypic analysis of the Leishmania infantum resistance to conventional drugs and new chemically synthesized compounds

Genotypic analysis of the Leishmania infantum resistance to conventional drugs and new chemically synthesized compounds

... several drugs became a problem in some endemic areas for ...for resistance. Furthermore, all the currently used antileishmanial drugs do not conjugate high efficiency, low toxicity and an affordable ...

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The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs

The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs

... drug-specific resistance, including for resistance to para-aminosalicylic acid and ...all drugs tested except pyrazinamide and para-aminosalicylic acid, with an overall concordance of ...

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Genotypic resistance mutations to antiretroviral drugs in HIV-1 B and non-B subtypes from Cuba

Genotypic resistance mutations to antiretroviral drugs in HIV-1 B and non-B subtypes from Cuba

... of resistance mutations to these drugs, as compared to the ...of resistance muta- tions to ZDV in these two patients with prolonged ZDV monotherapy treat- ment could be due to the suppression of the ...

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Venom peptides in association with standard drugs: a novel strategy for combating antibiotic resistance - an overview

Venom peptides in association with standard drugs: a novel strategy for combating antibiotic resistance - an overview

... antibiotic resistance that leads to resurgence of bacterial infections poses a threat to disease-free existence for humankind and is a challenge for the welfare of the society at ...standard drugs has ...

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Use and Misuse of Antimicrobial Drugs in Poultry and Livestock: Mechanisms of Antimicrobial Resistance

Use and Misuse of Antimicrobial Drugs in Poultry and Livestock: Mechanisms of Antimicrobial Resistance

... available drugs. It is therefore likely that cross–resistance will render the new drugs less ...New drugs that target new mechanisms of bacterial cell metabolism are ...

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In fluence of Treg cells and HBV genotype on sustained response and drug resistance in the treatment with nucleoside drugs

In fluence of Treg cells and HBV genotype on sustained response and drug resistance in the treatment with nucleoside drugs

... drug resistance are related to chronic hepatitis B virus ...nucleoside drugs and the virus’ genotype could be major factors in antiviral efficacy and drug resistance in patients ...

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Influenza A(H1N1)pdm09 Resistance and Cross-Decreased Susceptibility to Oseltamivir and Zanamivir Antiviral Drugs

Influenza A(H1N1)pdm09 Resistance and Cross-Decreased Susceptibility to Oseltamivir and Zanamivir Antiviral Drugs

... antiviral drugs available worldwide for the management of ...of resistance is continually threatening their use, rationalizing and highlighting the need for a close and sustained evaluation of virus ...

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Association of hepatitis C virus NS5B variants with resistance to new antiviral drugs among untreated patients

Association of hepatitis C virus NS5B variants with resistance to new antiviral drugs among untreated patients

... of resistance mutations associated with new HCV antiviral ...to resistance to a limited number of non-nucleoside inhibitor compounds ...about resistance mutations and there are few in vitro studies ...

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Resistance of Plamodium falciparum to Antimalarial Drugs in Zaragoza (Antioquia, Colombia), 1998

Resistance of Plamodium falciparum to Antimalarial Drugs in Zaragoza (Antioquia, Colombia), 1998

... same time of the year of the present study, we found in vivo resistance to CHL of 97%. Both studies were de- signed in a similar manner and identical measures were taken to avoid loss of patients and guarantee ...

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In Vitro Chloroquine Resistance Modulation Study on Fresh Isolates of Brazilian Plasmodium falciparum: Intrinsic Antimalarial Activity of Phenothiazine Drugs

In Vitro Chloroquine Resistance Modulation Study on Fresh Isolates of Brazilian Plasmodium falciparum: Intrinsic Antimalarial Activity of Phenothiazine Drugs

... of drugs reported as modulat- ing agents in resistant malaria and/or neoplastic multidrug-resistant cell lines were evaluated in Brazil- ian chloroquine-resistant fresh isolates of ...falciparum resistance ...

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Characterization of TRIB2-mediated resistance to anti-cancer drugs

Characterization of TRIB2-mediated resistance to anti-cancer drugs

... trials, drugs must be tested in cell lines, in this case preferably melanoma cell lines (in vitro model) and then in animal models (in vivo studies) and my project allowed me to test not only in cell lines, but ...

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Sex, drugs, bugs, and age: rational selection of empirical therapy for outpatient urinary tract infection in an era of extensive antimicrobial resistance

Sex, drugs, bugs, and age: rational selection of empirical therapy for outpatient urinary tract infection in an era of extensive antimicrobial resistance

... evident, particularly for complicated infections. Fourth, E. coli, although the single most common organism overall, overestimated aggregate susceptibility results, particularly for males and older women. These findings, ...

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PRIMARY RESISTANCE TO ANTITUBERCULOSIS DRUGS IN CHILE, 1978

PRIMARY RESISTANCE TO ANTITUBERCULOSIS DRUGS IN CHILE, 1978

... In 1978, a total of 1,694 patients with recently diag- nosed tuberculosis who had not been treated were sub- jected to sensitivity tests; 810 cases had been diag[r] ...

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Response to short-course chemotherapy of patients with initial resistance to antituberculosis drugs

Response to short-course chemotherapy of patients with initial resistance to antituberculosis drugs

... Among the study subjects, cases initially sensitive to all four drugs were less prone to treatment failure than those initially resistant to isoniazid or iso- niazid p[r] ...

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Bacteriologic study of a community water supply: detection of enterotoxigenic activity and resistance to antimicrobial drugs

Bacteriologic study of a community water supply: detection of enterotoxigenic activity and resistance to antimicrobial drugs

... (Strains included in group VIII on the basis of their resistance patterns were not found to contain any R-plasmids, indicating that the resistance genes involved [r] ...

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The Sensitivity and Resistance of Yeasts Isolated from Women with Vulvovaginal Candidiasis to Common Antifungal drugs Using Disc Diffusion

The Sensitivity and Resistance of Yeasts Isolated from Women with Vulvovaginal Candidiasis to Common Antifungal drugs Using Disc Diffusion

... Fluconazole and itraconazole susceptibility of vaginal yeast isolates from Slovakia... Multiple resistance mechanisms to azole antifungals in yeast clinical isolates.[r] ...

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Diabetes Drugs and Cardiovascular Safety

Diabetes Drugs and Cardiovascular Safety

... Insulin Resistance Intervention after Stroke (IRIS) trial, which included 3,876 nondiabetic patients with in- sulin resistance and ischemic stroke or transient ischemic at- tack, patients who were assigned ...

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