HCT-116
A versatile technique for the in vivo imaging of human tumor xenografts using near-infrared fluorochrome-conjugated macromolecule probes.
... tdTomato-expressing HCT 116 human colorectal cancer (T-HCT-116) cells by orange-red fluorescent protein tdTomato with the 535/600 nm filter set, the fluorescent signal from liver-metastasized ...
12
Structure and cytotoxic activity of terpenoidlike chalcones
... OVCAR-8-3 and 0.7 10 5 cells/ml for the HCT-116 strain.. Doxorubicin (5 lg/ml) and DMSO (0.05%) were used as pos- itive and negative controls, respectively. After 24 h, the terpenoid-like chalcones were ...
12
Terpene Esters from Natural Products: Synthesis and Evaluation of Cytotoxic Activity
... lines: HCT-116 (colon adenocarcinoma), SF-295 (glioblastoma) and OVCAR-8 (ovarian carcinoma) to evaluate the cell growth inhibition using the 3-(4,5- dimethyl- 2-thiazolyl-2,5-diphenyl-2H-tetrazolium ...
11
The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells.
... in HCT-116 colon carcinoma cells, HIF-1a and HIF-2b regulate the cancer metabolism by overlapping with the KRAS oncogene ...in HCT-116 cell line, that the levels of HIF-1a mRNAs are steady in ...
10
Synthesis of a new class of and evaluation of their potential as antitumoral agents
... lines HCT-116 (human colorectal carcinoma, ATCC # CCL-247), A-549 (human lung adenocarcinoma, ATCC # CCL- 185) and MDA-MB435 (human melanoma, ATCC # HTB-129) as well as against freshly prepared human blood ...
8
Synthesis and evaluation of cytotoxic effects of Aminoester derivatives of natural α , β Amyrin mixture
... The cytotoxicity was tested against HL-60 (human leukemia), HCT-116 (human colon) and PC-3 (human prostate) cancer cell-lines obtained from the National Cancer Institute, Bethesda (MD, USA). Cells were ...
8
Derivados modificados de tiossemicarbazonas e diclofenaco : perfil farmacológico e efeito da coordenação a metais
... sólido HCT-116 (carcinoma colorretal) e MCF-7 (carcinoma mamário), e contra leucemias HL-60 (leucemia mieloide) e Jurkat (leucemia ...de HCT-116 e ...contra HCT-116 que a ...
227
J. Braz. Chem. Soc. vol.28 número11
... carcinoma), HCT-116 (colon carcinoma) and HL60 (leukemia). HCT-116 and PC3 cell-lines showed weak tumor growth inhibition (range of ...
8
Spirostanol glucosides from the leaves of Cestrum laevigatum L.
... against HCT-116, OVCAR-8, HL-60 and SF-295 cancer cell lines showed formosanin C (5) as the most active against all cell lines, while compounds 1 and 2 showed moderated activity against ...
6
CoCl2, a mimic of hypoxia, induces formation of polyploid giant cells with stem characteristics in colon cancer.
... while HCT-116 control cells showed normal nuclear size and markers indicated normal disomy for chromosomes X (green), 18 (blue) and 21 (red), treatment with CoCl 2 , ...
10
A new and potent class of quinoline derivatives against cancer
... Compounds 5a–5i and 6a–6i (0.009–5 lg/cm 3 ) were tested for cytotoxic activity against three four cancer cell lines: SF-295 (glioblastoma), HCT-116 (colon), OVCAR-8 (ovarium), HL-60 (leukemia) (National ...
12
A new peptide ligand for targeting human carbonic anhydrase IX, identified through the phage display technology.
... line HCT 116 and on human umbilical vein endothelial cells ...in HCT 116 and HUVEC cells was investigated by quantitative real time ...
10
J. Braz. Chem. Soc. vol.26 número6
... N-8”-formyl-calycosidine and N-8”-methyl-N-1’-demethyl-iso-calycosidine, were isolated from the aerial part of Margaritopsis carrascoana, along with known calycosidine and hodgkinsine. The cytotoxicity of the isolated ...
8
Chemical composition of four essential oils of Eugenia from the brazilian Amazon and their cytotoxic and antioxidant activity
... and, previously, it was identified with a significant percentage in the oils of Guatteria diospyroides, G. oliviformis, and Unonopsis costaricensis. These Annonaceae oils showed remarkable cytotoxic activities against ...
10
J. Braz. Chem. Soc. vol.27 número12
... skeleton 1/2, 3/4 and 5/6 exhibited antimicrobial activity against Candida albicans, Candida krusei and Candida parapsilosis and cytotoxic activity against HCT-116, OVCAR-8, HL-60 and SF-295 cancer cell ...
11
Bioprospecção de compostos isolados de Combretum fruticosum com potencial em células tumorais in vitro
... Desse modo, a fim de verificar uma possível indução do processo autofágico pela trachelogenina em células HCT-116, foi realizada uma análise da expressão de proteínas relacionadas com a autofagia por meio ...
93
O papel dos proteoglicanos na adesão celular durante a tumorigênese: um modelo in vitro para o estudo da interação câncer-estroma
... Analisar a síntese de glicosaminoglicanos e proteoglicanos em linhagens de câncer colorretal (Caco-2 e HCT-116), durante a interação com a matriz extracelular de f[r] ...
50
Cytotoxic, antimigratory, pro-and antioxidative activities of extracts from medicinal mushrooms on colon cancer cell lines
... Our study showed that the tested mushroom ex- tracts had cell-selective effects – significant decrease of SW480 cells viability, wheras cytotoxic activity (IC50 <200 µg/mL) was only exhibited by PL and CS. As ...
13
Rev. bras. farmacogn. vol.21 número6
... on HCT 116 human colorectal carcinoma ...treated HCT 116 cells at sub-inhibitory ...of HCT 116 cells might prevent both primary and metastatic tumor growth in vivo which will be ...
10
J. Braz. Chem. Soc. vol.26 número8
... An asymmetrical dimer of kaurane diterpene and monoterpene and four novel diterpenes were isolated from the roots of Croton limae, along with kaempferol-3-O-glucoside, ombuin- 3-O-rutinoside and acetyl aleuritolic acid. ...
8