Methylation analysis
Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas.
... Paired specimens of leiomyoma and adjacent normal myome- trium were obtained from 10 Japanese women who had a single leiomyoma nodule to limit biological heterogeneity (Table 1). The women underwent hysterectomy, and ...
13
DNA methylation analysis of the macrosatellite repeat associated with FSHD muscular dystrophy at single nucleotide level.
... average methylation levels within 7 different D4Z4 regions, at single nucleotide ...for methylation analysis; [34]) software, setting a 95% cutoff for conversion in order to minimize the effect of ...
24
Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis.
... the methylation profiles at 11 regions that we predicted to be important in controlling the expression of transcription factors identified by ANOVA and in the enrichment ...The methylation plots for these ...
24
DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression.
... ACE methylation, have a protective effect on the development of ...DNA methylation patterns in the Figure ...their methylation status in the (2456/2255) region of the ACE ...
11
Genome-Wide DNA Methylation Analysis Identifies Novel Hypomethylated Non-Pericentromeric Genes with Potential Clinical Implications in ICF Syndrome.
... current analysis was performed by evaluating one lymphoblastoid (LCL) cell line and untrasformed fibroblasts derived from two different ICF patients with compound and different heterozygous mutations in DNMT3B ...
20
Sequence characterization, in silico mapping and cytosine methylation analysis of markers linked to apospory in Paspalum notatum
... An in silico mapping analysis of P. notatum apos- pory-specific sequences in the rice and maize genomes identified several orthologous sequences in segments of rice chromosomes 2 and 12, previously associated with ...
16
DNA methylation analysis of the tumor suppressor gene CDKN2B
... DNA methylation is a covalent modification and re- sults from the activity of a family of DNA methyltrans- ferase (DNMT) enzymes which catalyze the transfer of a methyl group (CH3) from S-adenosylmethionine (SAM) ...
7
H19DMR methylation analysis in patients with Beckwith-Wiedemann syndrome and isolated hemihyperplasia
... abnormal methylation of H19DMR because both effects have been described in neoplasias (principally Wilms’ tumor) in children with BWS (Bliek et ...abnormal methylation in the telomeric domain (H19DMR) may ...
4
Comprehensive analysis of gene expression and DNA methylation data identifies potential biomarkers and functional epigenetic modules for lung adenocarcinoma
... DNA methylation changes have been reported to occur early in carcinogenesis (Teschendorff et ...DNA methylation analysis seems to be a promising strategy in cancer ...integrative analysis of ...
8
MicroRNA promoter methylation: potential biomarkers in prostate cancer
... PCa remains one of the most prevalent neoplasms worldwide and constitutes a leading cause of morbidity and mortality by cancer in men. Due to PSA screening, improvements have been achieved in clinical management of this ...
101
DNA methylation pattern of apoptosisrelated genes in ameloblastoma
... discrepant methylation profile between tumours and controls were analysed by reverse-transcription quantitative PCR ...Lower methylation percentages of TNFRSF25 ...RT-qPCR analysis showed increased ...
5
Methylation-GC-MS analysis of arabinofuranose- and galactofuranose-containing structures: rapid synthesis of partially
... Methylation analysis of complex sugars pro- vides information on the substitution position of their glycosidic linkages. In this procedure the molecule can be first completely O-methylated by the methods of ...
12
Genome-wide DNA methylation patterns and transcription analysis in sheep muscle.
... DNA methylation plays a central role in regulating many aspects of growth and development in mammals through regulating gene ...resolution analysis of DNA methylation landscapes using methodology ...
7
The identification of specific methylation patterns across different cancers.
... DNA methylation is known as playing an important role in the ...DNA methylation patterns across cancers. High throughput DNA methylation analysis provides the possibility to comprehensively ...
16
Global DNA methylation of ischemic stroke subtypes.
... DNA methylation contribute to inter-individual phenotypic variation and are associated with cancer development and other complex diseases ...DNA methylation measurement ...statistical analysis and in ...
7
DNA Methylation Profile as a Tool for Lung Cancer Diagnosis & Subtyping.
... HOXA9 methylation levels comparing to ...promoter methylation levels for some genes might either represent an effect of aging, alterations due to previous therapy or contamination with tumor cells at ...
80
In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma.
... This analysis resulted in identification of 828 s-HMM, 763 m-HMM, and 582 l-HMM in U2OS cells (Table S1), and 641 s- HMM, 529 m-HMM, and 407 l-HMM regions in MG63 cells (Table ...
16
DNA methylation, environmental exposures and early embryo development
... DNA methylation patterns and induce permanent changes to the developmental program, leading to the onset of adverse health outcomes in ...DNA methylation can occur as a response to environmental cues, ...
10
DNA methylation regulates expression of VEGF-C, and S-adenosylmethionine is effective for VEGF-C methylation and for inhibiting cancer growth
... DNA methylation and histone modification rather than changes in DNA ...DNA methylation plays a critical role in regulating and reprogramming gene expression patterns in mammalian cells ...numerous ...
8
Morphologi cal analysis and DNA methylation in
... Even with little genetic diversity, the phenotypes of C. bonariensis showed differences in several morphological characteristics. Similar results were also found by Richards et al. (2008), in Fallopia japonica (Houtt.) ...
12