[PDF] Top 20 Arq Bras Endocrinol Metab vol.56 número9

... A leptina, uma adipocina produzida principalmente pelo tecido adiposo branco, tem um pa- pel importante não somente na regulação da ingestão alimentar, mas também no controle da imunidade e da inlamação. Já foi ... See full document

... Objective: To verify if the frequency of spontaneous pubertal development among girls with Tur- ner syndrome (TS) diagnosed in infancy and childhood is greater than that of patients diagno- sed later. Subjects and ... See full document

... Ao longo de sua vida colecionou merecidos títulos: Membro Titular da Academia Nacional de Medicina e da Academia de Medicina do Estado do Rio de Janeiro, Livre-Docente da UFRJ, Profes[r] ... See full document

... The disposition of anabolic and catabolic hormones to inluence protein turnover and, in turn, their inluence on the structural status of skel- etal muscles, led us to speculate as to wh[r] ... See full document

... Many cases have been published showing a co-existence of autoimmune thyroid diseases (AITDs) and other autoimmune diseases. About a quarter of patients with achalasia have a con- current thyroid disease, most commonly ... See full document

... Tumores ovarianos virilizantes são uma causa rara de hiperandrogenismo em mulheres, con- tabilizando menos de 5% de todos as neoplasias ovarianas. Esses tumores ocorrem mais co- mumente em mulheres em peri ou ... See full document

... Objective: To investigate the presence of variants in the TAC3 and TACR3 genes, which encode NKB and its receptor (NK3R), respectively, in a large cohort of patients with idiopathic central pubertal disorders. Subjects ... See full document

... In conclusion, our study, using a formal Bayesian methodology, presented the numeric expression of in- tuitive clinical estimation of pretest probability of CS diagnosis, whose mean is estimated in 51%. In addition, ... See full document

... Objectives: To investigate thyroid peroxidase gene (TPO) mutations in a Chinese siblings with congenital goitrous hypothyroidism (CGH). Subjects and methods: The proband, his sister, and their parents were enrolled. All ... See full document

... Student’s t test, and ANOVA, at a 5% signiicance level. Results: The average age was 56.7 years-old; 76.3% had dyslipidemia, 24.4% pre-diabetes (PDM), 10.7% type 2 diabetes mellitus (T2DM), 46.6% hypertension, 52.7% ... See full document

... 7. Ejaz S, Vissilopoulou-Sellin R, Busaidy NL, Hu MI, Waguespack SG, Jimenez C, et al. Cushing syndrome secondary to ectopic ad- renocorticotropic hormone secretion: the University of Texas MD Andersen Cancer Center ... See full document

... Objective: The rate of reduction of nocturnal blood pressure (NBP) is lesser than normal in patients with type 2 diabetes mellitus (type 2 DM). Hyperhomocysteinemia (HHC) disrupts vascular structure and function, no ... See full document

... The enzyme 17b-hydroxysteroid dehydrogenase type 3 (17-b-HSD3) catalyzes the conversion of androstenedione to testosterone in the testes, and its deiciency is a rare disorder of sex devel- opment in 46,XY individuals. It ... See full document

... A síndrome de Frasier (SF), caracterizada por disgenesia gonadal e nefropatia, é causada por mu- tações especíicas no gene supressor do tumor de Wilms (WT1) localizado em 11p23. Pacientes com cariótipo 46,XY apresentam ... See full document

... Maturity-onset diabetes of the young (MODY) is characterized by an autosomal dominant mode of inheritance, early onset of hyperglycemia, and defects of insulin secretion. MODY subtypes described present genetic, ... See full document

... Destaco, também, que esse efeito parece ser independente do tempo, mas sim regulado pela disponibilidade de acetil-CoA e citrato durante o metabolismo de lipídeos, favorecendo o ciclo [r] ... See full document

... Objetivo: Estudar a prevalência de dor e disfunção do ombro em pacientes com diabetes me- lito (DM) do sul do Brasil e veriicar a possível associação com controle glicêmico e fatores epidemiológicos. Sujeitos e métodos: ... See full document

... Relatamos uma nova mutação no gene GNRHR em um homem com hipogonadismo hipogo- nadotróico isolado normósmico (HHIn). A região codiicadora do gene GNRHR foi ampliicada e sequenciada. Três variantes p.[Asn10Lys;Gln11Lys]; ... See full document

... It is well established that genetic factors play an important role in the development of both type 2 diabetes mellitus (DM2) and obesity, and that genetically susceptible subjects can develop these metabolic diseases ... See full document

... Objetivo: Realizamos um estudo prospectivo avaliando a prevalência de patologia nodular tireói dea em 34 pacientes acromegálicos. Sujeitos e métodos: Avaliamos os pacientes com ecograia tireóidea e punção biópsia com ... See full document