Top PDF Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice.
Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice.
... male diabetic db/db (DM) mice and non- diabetic db/+ control (Cn) mice were obtained from Charles River, Calco, Italy (strain from Jackson mice: ...wks of age, the ...
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Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake.
... ventricle hypertrophy (LVH) constitutes a major risk factor for heart ...LVH is most commonly caused by chronic elevation in arterial blood pressure, reduction of blood pressure to ...
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Kruppel-like factor 2 is required for normal mouse cardiac development.
... Kru¨ppel-like factor 2 (KLF2) is expressed in endothelial cells in the developing heart, particularly in areas of high shear stress, such as the ...
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Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
... Klotho, the exact pathophysiologic mechanisms behind its association with CKD progression are yet to be ...which is mainly produced by the kidneys, consists of a long extracellular domain ...
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The PKD inhibitor CID755673 enhances cardiac function in diabetic db/db mice.
... The development of diabetic cardiomyopathy is a key contributor to heart failure and mortal- ity in obesity and type 2 diabetes ...on the development ...
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FTO is a relevant factor for the development of the metabolic syndrome in mice.
... for the production of insulin during insulin resistance and hyperglycemia can result to beta cell hypertrophy and proliferation, and finally to enlarged ...isolated the pancreas and stained ...
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Alteration of the thymic T cell repertoire by rotavirus infection is associated with delayed type 1 diabetes development in non-obese diabetic mice.
... determine the effect of RRV infection in infant mice on their T cell function as adults, the proliferative response by PLN cells was ...NOD mice were mock- or RRV-infected as ...
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The role of business intelligence in decision process modeling
... Figure 2 shows the dialog box for assigning the signii cance of each criterion related to others in the predei ned ...tions is Saaty’s most famous scale for assigning ...
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Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants
... as hypertension (8), myocardial infarction (9) and heart failure (10), local cardiac RAS levels are increased by augmented protein, angiotensino- gen (AGT), angiotensin-converting enzyme (ACE) and Ang II, ...
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Linoleic acid-induced mitochondrial Ca(2+) efflux causes peroxynitrite generation and protein nitrotyrosylation.
... reported the expression of endothelial NOS (eNOS) and inducible NOS (iNOS), but not neuronal NOS, in rat mesangial cells ...[29]. The eNOS and iNOS expressed in mesangial cells may be ...
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A new metabolomic signature in type-2 diabetes mellitus and its pathophysiology.
... Subjects in this study were selected from 87,033 regular and long-term blood donors at the blood bank of the Bavarian Red ...Cross. The study included both a prospective and a ...
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ANTI-COLLAGEN TYPE IV ANTIBODIES AND THE DEVELOPMENT OF MICROVASCULAR COMPLICATIONS IN DIABETIC PATIENTS WITH ARTERIAL HYPERTENSION
... object of the study of Yano et al. 1997 [16] was to evaluate the serum 7S domain of type IV collagen (7S- collagen) levels in patients with essential hypertension ...
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Duration-controlled swimming exercise training induces cardiac hypertrophy in mice
... for the study of molecular mechanisms underlying exercise-induced car- diac ...apparatus is described to control training regimens in terms of duration, load, and frequency of ...
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Joint Analysis of the Discount Factor and Payoff Parameters in Dynamic Discrete Choice Games
... identi…ed, in a closed-form, independently of the discount factor and speci…cation of the remaining components of the payo¤ ...on the payo¤s as well as ...
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Pulmonary function, cholinergic bronchomotor tone, and cardiac autonomic abnormalities in type 2 diabetic patients
... from the Ribeirão Preto general community as a normal control group. The male/female ratio was 8/9 for both diabetic and control ...subjects. The in- clusion criteria for the ...
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Salivary Output in Type 2 Diabetic Patients
... In this study, xerostomia was evaluated using a ‘multi- item’ inventory comprising nineteen questions which included those eliciting the subjective symptoms of the patients such as dry[r] ...
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Agregação familiar e resultados maternos e perinatais da pré-eclâmpsia severa em população do Rio Grande do Norte
... grade of hepatic involvement varied from a minor capsular laceration to extensive parenchymal ...rupture. The majority of the hepatic lesions were found in the right ...One ...
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What is the role of apelin regarding cardiovascular risk and progression of renal disease in type 2 diabetic patients with diabetic nephropathy?
... approached the association of apelin levels with renal disease and cardiovascular risk ...with the renal function parameter ...be in accordance with a previously reported study [12] that has ...
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Impaired virus clearance, compromised immune response and increased mortality in type 2 diabetic mice infected with West Nile virus.
... induction of antiviral immune responses is critical for the control of WNV infection ...IFN-a is rapidly produced following WNV infection and is critical for controlling virus ...
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J OÃOR ODRIGUESF ERREIRAR
... phosphorylation in response to insulin (Chapter III, Figure 3.6). The presence of InsRs was also confirmed on finding that isolated whole CBs incubated with insulin accumulate more ...
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