[PDF] Top 20 Synthesis of 2,3Diyne1,4 derivatives and evaluation of cytotoxic activity against tumor cell lines
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Synthesis of 2,3Diyne1,4 derivatives and evaluation of cytotoxic activity against tumor cell lines
... with 4-methoxyphenylacetylene afforded compound 2b with 46% ...reactivity, and this reaction occurred two times faster than that from unsubstituted phenyl (entry 2, Table ...2d and 2e with ... See full document
7
Synthesis and evaluation of cytotoxic effects of Aminoester derivatives of natural α , β Amyrin mixture
... pharmacological activity of pentacyclic triterpenes (α,β-amyrins), and due to the fact that the modification of the rings usually requires multi- step sequence of chemical ... See full document
8
Rev. bras. farmacogn. vol.26 número4
... polyphenolic and sulphur contents of the aerial parts of Capparis spinosa ...positions of the water distilled essential oil were investigated by GC/MS analysis where the major constituent ... See full document
7
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
... prostate and renal cancers, as well as cell lines established from human melanoma, pleuramesothelioma and the uteri ...K252c and arcyriaflavin A were isolated from actinomycete strain ... See full document
21
Synthesis and cytotoxic evaluation of a series of 2amino against human cancer cells
... Quinones and their derivatives are substances naturally obtained or synthesized in the laboratory [2] with multiple biological functions in the metabolic cycles of various organisms ... See full document
12
Evaluation of the cytotoxicity of structurally correlated pmenthane derivatives
... The cytotoxic activity of the eighteen monoterpenes was evaluated against several human tumor cell lines: HCT-116 (colon), OVCAR-8 (ovarian), and SF-295 ... See full document
17
Synthesis and evaluation of ( ) and analogues as potential anticancer and antiinflammatory agents
... better cytotoxic activities against some of the tested cell lines (Table 2, entries 5 and ...good cytotoxic activity against lung can- cer cells ... See full document
10
Liriodenine (9): Yellow amorphous powder (CHCl3 ); identified
... investigation of the alkaloid-rich fraction obtained from the leaves of Guatteria pogonopus ...isolation and identification for the first time in this species of: (+)-nornuciferine (1), a ... See full document
7
Arylated and dihydrofuran : , evaluation of antitumor activity and their correlation
... 1 and Fig. 3 showed that both 1,2-naphthoquinones and 1,4-naphthoquinones have proven to be active against various cell lines with an emphasis on substances 6a, 6c–f (ortho ... See full document
7
Terpene Esters from Natural Products: Synthesis and Evaluation of Cytotoxic Activity
... classes of natural compounds or its derivatives are esters (Azimova ...class of compounds shows variety of structural types leading to a wide spectrum of biological activity, ... See full document
11
J. Braz. Chem. Soc. vol.26 número7
... course of our continuing search for potential lead compounds from Korean traditional medicinal plants, we investigated the MeOH extract of ...stems and isolated three new ursane triterpene saponins ... See full document
7
J. Braz. Chem. Soc. vol.26 número8
... CC and eluted with increasing amounts of EtOAc in hexane (9:1 to 1:9) to obtain 23 fractions (A1-A23), in which A11-A13 displayed cytotoxic ...MeOH and purified by preparative TLC on SiO ... See full document
5
J. Braz. Chem. Soc. vol.26 número4
... spectroscopy and heteronuclear multiple-bond correlation spectroscopy) and spectrometric (high resolution electrospray ionization mass) ...the cell viability of tumor cell ... See full document
6
Rev. bras. farmacogn. vol.27 número5
... China and Japan and cultivated in Brazil where is popularly known as falso-cardamomo, pacová, gengibre-concha, and colônia (Lorenzi and Matos, 2002; Lorenzi and Souza, ...flowers ... See full document
7
J. Braz. Chem. Soc. vol.20 número10
... for 2 h at 37 ºC. After infection, cells were washed and dispensed in a 96-well plate in the presence of various drug ...triplicate, and wells treated with AZT were also monitored as controls ... See full document
20
Synthesis and evaluation of the phytotoxic activity of α-Santonin derivatives.
... SYNTHESIS AND EVALUATION OF THE PHYTOTOXIC ACTIVITY OF α-SANTONIN ...Mixtures of α-Santonin and various solvents were irradiated by either high or low pressure ... See full document
6
Pharmacological characterization of cnidarian extracts from the Caribbean Sea: evaluation of anti-snake venom and antitumor properties
... use of genomic and proteomic approaches had per- mitted a rapid increase in the number of sequences from cnidarians deposited in protein and gene databases [30 – ...Some of these toxins ... See full document
11
Synthesis and biological evaluation of mono and bis-naphthalimide derivatives against SH-SY5Y, human brain cancer cells
... idea of synthesizing this type of compounds has stimulated by the idea that the pharmacological activity of intercalating drugs can be significantly increased with higher DNA binding constants ... See full document
169
Quím. Nova vol.31 número1
... flasks and maintained in continuously exponential growth were detached with ...(PBS) and washed 3 times with RPMI medium at 1000 rpm/15 min/10 ...density of 1×105 cells per well. After 24 h of ... See full document
5
Searching for innovative antitumoral drugs in marine microalgae
... habitats of the South of Portugal (Algarve) were screened for anti-cancer properties against THP-1 cell line, none of them showed toxicity to these cells, with cell viabilities ... See full document
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