[PDF] Top 20 Circulating cell-free DNA as a biomarker in the diagnosis and prognosis of colorectal cancer

... Colorectal cancer (CRC) is a disease without evident clinical symptoms in early stages, leading to late diagnosis and disease ...diagnostic and prognostic tools require invasive ... See full document

... Members of the heterochromatin protein 1 family (HP1α, β and γ) are mostly associated with heterochromatin and play important roles in gene regulation and DNA damage re- ... See full document

... helicase DNA-binding proteins (CHDs), including CHD 1-8, were associated with several human diseases and cancers including lymphoma, liver cancer, colorectal cancer, stomach ... See full document

... studies of the Guardant360 cfDNA panel highlight its differences from both solid tumor and other cell-free circulating tumor DNA genomic testing ...methods. The ... See full document

... levels of mtDNA were detected in plasma of prostate cancer patients using quantitative real-time PCR amplification (Mehra et ...mtDNA in serum of patients with pros- tate ... See full document

... 19 and is non-tissue-specifically and ubiquitously expressed in a wide range of cell ...splicing, the E2A gene encodes two isoforms, E12 and E47 (collectively referred as ... See full document

... non-invasive and convenient biomarker. Colorectal cancer is, if detected early, a highly curable ...that the decrease in CRC incidence rates is largely duo to colonoscopy ... See full document

... months. The diagnosis of recurrence was based on the imaging method and biopsy (if possi- ...duration of 59 months. Overall survival (OS) was defined as the time from ... See full document

... differences of baseline characteristics between groups were analyzed using the x 2 test for categorical data, followed by application of Yates’ correction and the Mann- Whitney U test ... See full document

... Mandel and Metais were the first to describe their observation of the presence of extracellu- lar nucleic acids in humans ...found in cell-free nucleic acids ... See full document

... ABSTRACT: Colorectal neoplasm is one of the most common cancers in developed countries and its incidence has grown ...progressively. The currently used attempts to prognostic ... See full document

... (qPCR) of β-cell-derived DNA in the blood can serve as a biomarker of β-cell death in ...β-cells in the islet. Here we examined whether ... See full document

... household, the program caused an increase of more than 11 percentage points in the probability of attending ...increase in the estimated impact is the fact that ... See full document

... expression of NGAL (acronym for neutrophil gelatinase associated lipocalin), a 25 kDa secreted glycoprotein, in PanIN-1s, the earliest premalignant lesions preceding ...noted in a limited set ... See full document

... Evaluation of the association between REG4 expression and clinicopathological parameters or MUC expressions was done by the exact Pearson chi-square test or the exact linear-by-linear ... See full document

... From the analysis, it was found that lands were acquired majorly by inheritance and the resultant effect of this is the fragmentation of land during the acquisition ... See full document

... support the management of coastal areas, so it can be arranged on the setting, management, utilization, preservation and protection and security of marine areas and ... See full document

... on the surface with the electric arc with the use of the FALTIG 315AC/DC ...apparatus. The single remelting was applied. The treatment parameters were used: amperage ... See full document

... from the National Household Survey (Pesquisa Nacional por Amostra de Domicílios – PNAD/IBGE) from 1995 to 2009, conducted by the Brazilian Institute of Geography and Statistics 3 .... ... See full document

... problems, in this paper we rely on a large panel of matched employer- employee ...by the federal government in Brazil (Rela¸c˜ao Anual de Informa¸c˜oes Sociais - RAIS ), the data ... See full document